Truth Behind Mifepristone Shedding the Endometrial Lining for Abortion

Medication pregnancy termination is a non-invasive healthcare process. It is undoubtedly safe for women who are pregnant up to 9 weeks of gestation. A combination of medicine helps to end the pregnancy, with an efficacy rate of 95-99% on taking Mifepristone and Misoprostol pills. While most of us are aware that Misoprostol pills dispel the pregnancy portions from the womb through uterine contractions, not many understand the concept behind the Mifepristone medication. Do remember that it is the primary pill in the procedure and plays a vital role.

In this post, we will talk about how Mifepristone abortion pills bring the pregnancy to a stop by shedding the uterine lining.

What is Endometrial Lining in the Uterus?

The endometrial lining is basically a coating in the uterus. Here is the purpose of it and the function to expect:

• For a woman, the release of an egg from the ovaries every month is a part of the expected menstrual cycle. In this time, it thickens so as to prepare for the implantation of an embryo. The fertilized egg attaches to the uterus wall, leading to a pregnancy.
•  But if the egg does not fertilize, the endometrial lining exits the body by shedding. This causes menstrual bleeding.
•  If the endometrial is less than 7mm, then it cannot hold a fertilized egg. In such a case, even after implantation, natural miscarriage may occur.
•  Or, the woman may encounter fertility issues. Now you understand that the thickness of endometrial lining and its presence are required for the pregnancy to stay stable.
•  The uterine lining after all aids in the sustenance of the embryo and offers nourishment to it to let the pregnancy advance further.

Is Endometrial Lining Necessary to Keep a Pregnancy Going?

A group of cells forms the endometrial lining that is based inside the uterus. It is essential for an intrauterine pregnancy and exists in the first trimester. As the pregnancy moves to the second trimester, it is replaced by the placenta. But until then, the uterine lining prevents the detachment of the fertilized egg from the womb. If you menstruate every month, it means the thickened endometrium does not find the egg to implant and sheds to cause a period.

Once you conceive, progesterone hormone increases in the body to keep the endometrial lining intact. The uterine lining has two layers. And these layers are visible in the uterus scan by an ultrasound. There is a functional layer that breaks during menstruation. Then a permanent basal layer also exists. A healthy endometrial lining creates a welcoming environment at the time of ovulation.

So, if you get pregnant, the endometrium does not permit the uterus wall to stick together. Rather, the lining reacts to estrogen and progesterone hormones and gets thicker. After pregnancy, the endometrial develops connections with the placenta. It gives a rich blood supply so that the fetus receives nutrients and other necessities to stay implanted and grow.

Why is a Thick Uterine Lining Important for a Pregnancy?

The uterine wall has a layer of the mucus membrane, and endometrium to let a pregnancy last. The thickness of the second layer of the uterine lining is crucial, which is about 1mm in the womb. But when ovulation begins, new functional layers are formed due to the development of cells. It helps the endometrial lining to get thicker and accept a fertilized egg for implantation. For a pregnancy to survive, the thickness of the layer should be between 8 and 15mm. The thickness of the endometrial varies from one female to another.

How Does Mifepristone Break the Endometrial Lining?

We ran into a detailed explanation about what endometrial lining is and its requirement for a pregnancy to keep going. However, when you want to terminate a pregnancy, the procedure is all about reversing the existence of the uterine wall, so that the implantation cannot stay. Here is where the abortion pill steps in:

• The Mifepristone pill is efficient to undo the chances of being pregnant by shedding the endometrial lining. It does so by creating a lack of progesterone hormone supply.
• As the progesterone hormone is needed to form the cells of the uterine lining, the less amount available results in the breaking of the endometrium.
• The anti-pregnancy hormone action lets the embryo and pregnancy tissues come away from the uterus wall. The pregnancy does not develop anymore. And due to the pregnancy portions remaining in the womb, the expulsion of these is induced by Misoprostol pills.

Final Words

Mifepristone is a potent medication to bring an unexpected pregnancy to end. It sheds the endometrial lining to help with pregnancy termination. By understanding the function of the uterine lining and why it is necessary to get it broken during an abortion, you now know the importance of the anti-progesterone pill.