How does Mifepristone pill work to block Progesterone hormone

Mifepristone is an abortion pill that stops the production of progesterone hormone for the time being. This causes the endometrial lining to break. Once this lining sheds, the attached embryo and pregnancy sections come off from the uterus wall. Thus, the pregnancy also experiences a permanent halt, due to which, the pregnancy cannot continue to advance. You need to take the Mifepristone pill 200 mg orally with water on day 1. It cannot alone expel the pregnancy portions out of the womb.

You have to use the anti-progesterone abortion medication with prostaglandin E1 analog pills known as Misoprostol. You will require 200mcg x 4 pills to be taken 24 to 48 hours after Mifepristone or Mifeprex intake. The anti-progesterone medicine is also available as Generic RU486. If utilising buccally, place the Misoprostol pills in both cheek pouches or under the tongue so they dissolve before intake of the melted contents orally.

If utilising Misoprostol vaginally, put the pills in the vagina and lay down for half an hour. The dissolved medicine will get absorbed in the uterus. Mifepristone may not cause any bleeding or side effects. But after the use of the secondary abortion pills, you can expect heavy bleeding to begin within 2 to 4 hours.

Effects of Mifepristone and Other Abortion Pills

Mifepristone prepares you for an abortion by ending the pregnancy. But the conception parts remain in the uterus itself until labor is induced by medicine to empty the uterus. Misoprostol leads to uterine contractions and helps to remove the products of conception from the womb. It is accompanied by cramps giving rise to pain in the abdomen, waist, back, legs, and elsewhere. The pill also widens the cervix for assisting in the exit of the pregnancy portions from the womb.

Avoid heavy exercise, physical activity, and stress during pregnancy termination. You can manage the temporary side effects with medicine and care. Use large sanitary pads for the bleeding. Do not insert menstrual cups or tampons. Take anti-emetic medicine for nausea and vomiting. Drink lots of water if you have diarrhoea. In case of dizziness, rest well and do not move about much to avoid tripping anywhere. Stay in bed and the comfort of your privacy.

How Does Progesterone Hormone Help a Pregnancy?

Now that you understand that the anti-progesterone medication – Mifepristone is vital in abortion, you must also be curious about the function of the progesterone hormone and how it sustains a pregnancy. We will explain the facts right here:

• Progesterone is a hormone that the placenta, ovaries, and adrenal glands naturally produce during pregnancy. It assists in the implantation of the fertilized egg. So, the embryo stays attached to the uterus wall to keep the pregnancy ongoing in the presence of progesterone.
• You must have heard about progesterone treatments for fertility and medicines for those with problems during pregnancy. But anti-progesterone pills do the opposite. For instance, Mifepristone restricts the hormone so that the uterus wall detaches the embryo from it.
• The hormone progesterone is produced in early pregnancy by the Corpus Luteum. This ovarian follicle keeps the progesterone in existence in the first trimester, after which the level of the hormone starts to reduce as the placenta takes over.
• The pregnancy hormone creates a well-balanced environment for the ovaries and the uterus to relax the muscles and aid the immune system to not combat the DNA. As a result, the pregnancy thrives and transcends to the second trimester.
• The progesterone hormone also causes the luteal phase to start and then thickens the uterus lining to receive the embryo and keep it secured in the endometrial. It thus aids in the growth of the fetus as the pregnancy advances ahead.

But the Mifepristone abortion pill is effective only in the first trimester. It works against progesterone, while Misoprostol creates natural miscarriage-like conditions. This is the reason why medical pregnancy termination is effective only for intrauterine pregnancies that too within 9 weeks of gestation. Thus, you can use the medicines at home by following the advice of your healthcare provider and experience a complete end to your unplanned pregnancy without troubles.

To Conclude

Our body works in ways that science can only explain. And some functions are too complicated to understand, and this is where we step in to decode what keeps the pregnancy going through progesterone hormone, and how the abortion pill, Mifepristone safely terminates it with the assistance of another medication, Misoprostol or Cytolog.